Tehran University Develops Nanocapsule Drug Release Methods
Iranian chemists at Tehran University have been experimenting with drug release using various types of nanocapsules. Recently they have developed a polymer nanocapsule for administering Penicillin-G. From the article at Farsnews:
“Among the present nanoparticles, nanocapsules and micelle nanoparticles are more effective. Micelle nanoparticles release the drug in the body slowly, because of their interaction with central hydrophobe of nanoparticle, but nanocapsules, because of their thin layer, release the drug faster,” said Sepideh Khoee, an academic member of Tehran University and member of the research team.
“In this project, we succeeded in synthesizing a polymer nanocapsule for releasing Penicillin-G in body,” she continued.
The important point in this project is the dominant role of surfactants in making the preliminary and final emulsion.
Khoee explained that the size of nanoparticles will change by changing the amount and the kind of surfactants and in this project, 75 nanometer nanoparticles were produced by changing the kind and amount of two surfactants ‘Tween’ and ‘Span’.