Development of a novel nanocapsule formulation by emulsion-diffusion combined with high hydrostatic pressure
Abstract: A common method used to prepare polymeric nanoparticles in pharmaceutical technology is emulsion-diffusion. However, this method has several disadvantages due to the long duration of the process. At the diffusion step of conventional emulsion-diffusion, high pressure treatment could replace the addition of great quantities of water resulting in diffusion of the solvents from the internal [...]